Past Project: Epigenetic Readers

Structural and molecular studies on BPTF and GAS41.

Part of my thesis titled “A Structural Approach to Protein Intrinsic Versatility – the Tale of Succinyllysine Reader GAS41 and Palmitoyllysine Eraser SIRT3”.

Publication

Wang Y, Jin J, Chung MWH, Feng L, Sun H, Hao Q. Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation. 2018. Proc Natl Acad Sci U S A. 115(10):2365-2370. DOI: 10.1073/pnas.1717664115.

To be updated.